Latest Posts
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Association of mental health conditions and functional gastrointestinal disorders among Vietnamese new-entry medical students
Functional gastrointestinal disorders (FGIDs), sometimes called disorders of gut–brain interaction, do not affect only older people, they are also common in young adults. A study among 400 first-year medical students in Vietnam investigated how these gut disorders relate to mental health. About 10% of students had an FGID such as functional dyspepsia or irritable bowel…
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Systematic review and meta-analysis of performance of wearable artificial intelligence in detecting and predicting depression
The systematic review and meta-analysis found that wearable AI systems demonstrate promising performance in detecting and predicting depression. However, substantial variability exists among algorithms and devices, thereby indicating that performance can vary significantly. What this means is that disparities across different algorithms and devices were identified, suggesting that certain demographic groups may be underrepresented or inadequately served…
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Helicobacter Pylori Associated Depression among Patients Presenting with Epigastric Pain
Helicobacter pylori infection is an extremely prevalent infection that has been connected not only to a number of illnesses such as stomach cancer and peptic ulcer disease. H. pylori has also been linked to depression…
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Depression among people with dyspepsia and H. pylori infection: A community based cross-sectional study in Ethiopia
A 2022 community-based study in southwest Ethiopia explored potential links between Helicobacter pylori infection, dyspepsia, and depression in residents aged 13 years and older. Among the 871 participants – most of whom were married, had…
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Digital health tools for the passive monitoring of depression: a systematic review of methods
This systematic review examines studies linking passive data from smartphones and wearables to depression, identifying key methodological flaws and threats to reproducibility. It highlights biases such as representation, measurement, and evaluation bias, stemming from small,…
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Rapamycin Attenuates Anxiety and Depressive Behavior Induced by Helicobacter pylori in Association with Reduced Circulating Levels of Ghrelin
In this experimental study, researchers investigated how H. pylori infection influences depression-like behavior and certain biological markers in mice, focusing especially on the hormone ghrelin. Mice infected with the bacteria showed more anxiety- and depression-like behaviors in standard laboratory tests compared with healthy mice. They moved less, showed more signs of stress, and had lower preference for sweet solutions, a common indicator of loss of pleasure.Biologically, H. pylori infection led to reduced circulating ghrelin levels and activation of the mTOR signaling pathway in the stomach. It was also associated with increased markers of brain inflammation and cell injury in the…
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Bias Discovery in Machine Learning Models for Mental Health
This article examined how AI can unintentionally reproduce social and demographic biases when applied to mental health prediction. Using benzodiazepine prescriptions as a proxy for conditions such as depression and anxiety, a study analyzed machine learning models trained on patient data to identify systematic disparities. It found that women are more frequently predicted to…
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Increased risk of short-term depressive disorder after Helicobacter pylori eradication: A population-based nested cohort study
A study using Taiwan’s National Health Insurance data found that antibiotic therapy for H. pylori in patients with peptic ulcer disease was linked to a short-term increase in psychiatrist-diagnosed depression within 30 days. Women and patients…
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GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression
A study of over 450,000 people in the UK Biobank identified 8 independent genes that affect stomach acid, gut movement, and the body’s response to infection, including susceptibility to Helicobacter pylori infection. The study also explored…
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Helicobacter pylori Infection Is Associated with Long-Term Cognitive Decline in Older Adults: A Two-Year Follow-Up Study
Helicobacter pylori infection is usually known for causing stomach problems, but it may also affect brain health. This research study published in 2023 followed 268 older adults with memory complaints for two years to see whether…