A study of over 450,000 people in the UK Biobank identified 8 independent genes that affect stomach acid, gut movement, and the body’s response to infection, including susceptibility to Helicobacter pylori infection.
The study also explored connections between these gut conditions and depression, which often occurs alongside digestive problems, providing new insights into the complex interplay between gut health and mental well-being.
Learn more about this study here: https://doi.org/10.1038/s41467-021-21280-7
Reference
Wu, Y., Murray, G.K., Byrne, E.M. et al. GWAS of peptic ulcer disease implicates Helicobacter pylori infection, other gastrointestinal disorders and depression. Nat Commun 12, 1146 (2021)