Health Citizens – European Research Institute

Tag: HPA Axis

  • Association of Helicobacter pylori Infection with Depression and Anxiety: A Systematic Review and Meta-Analysis

    Association of Helicobacter pylori Infection with Depression and Anxiety: A Systematic Review and Meta-Analysis

    The association between Helicobacter pylori infection and depression and anxiety has been reported in the literature.

    A meta-analysis was developed in 2024 with the aim of investigating the association between H. pylori infection with these mental health conditions. The systematic search was conducted not only in international sources such as PubMed, Web of Science, and Embase, but also in Chinese databases, and looked for observational studies that reported the incidence or prevalence of depression and anxiety in patients with H. pylori infection.

    Surprisingly, while the findings of this analysis showed a significant positive association between the bacteria and anxiety disorders, the association with depression appeared to be insignificant. Nevertheless, this finding seems to imply that clinicians treating H. pylori patients should also address their psychological well-being.

    Learn more about this review here: https://doi.org/10.1155/2024/9247586

    Reference

    Li, Lu, Ren, Yadi, Wang, Zeyu, Niu, Yanqing, Zhao, Ying, Aihaiti, Xiaherezhati, Ji, Yinglan, Li, Man, Association of Helicobacter pylori Infection with Depression and Anxiety: A Systematic Review and Meta-Analysis, International Journal of Clinical Practice, 2024, 9247586, 9 pages, 2024.

  • Psychological effects of Helicobacter pylori-associated atrophic gastritis in patients under 50 years: A cross-sectional study

    Psychological effects of Helicobacter pylori-associated atrophic gastritis in patients under 50 years: A cross-sectional study

    A cross-sectional, observational study involving 975 Japanese individuals who underwent a health checkup, has found that people with atrophic gastritis had a significantly higher risk of experiencing psychological distress or depressed mood.

    Interestingly, the risk was higher in females under 50 years old, regardless of H. pylori infection status.

    Although the mechanism remains to be elucidated, the researchers suggest there is a possibility that nutritional status, neuroendocrinologic factors, and/or socioeconomic factors are involved. However, further studies are necessary to reveal the precise underlying mechanisms.

    Learn more about this study here: https://doi.org/10.1111/hel.12445

    Reference

    Takeoka A, Tayama J, Kobayashi M, et al. Psychological effects of Helicobacter pylori-associated atrophic gastritis in patients under 50 years: A cross-sectional study. Helicobacter. 2017; 22:e12445